Focal hyperhidrosis is defined as the excessive secretion of sweat by the secretory sweat glands. It mainly affects the armpits, palms, soles, and face and is due to a disorder of the sympathetic nervous system.
Available treatment options include topical application of solutions, iontophoresis, systemic anticholinergics, and surgical skin removal or sympathectomy.
Recently, chemical denervation of the sweat glands of the affected area with intradermal administration of botulinum toxin has been added to the therapeutic solutions.
Botulinum toxins are a group of neurotoxins with A-G serotypes that inhibit the presynaptic release of acetylcholine.
The results of the use of the substance show that the botulinum toxin is a promising treatment for focal hyperhidrosis, an alternative to aggressive surgical methods and less effective topical applications.
Dose personalization and improved administration techniques can relieve patients of such annoyance.